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These medications are generally considered for adults with: BMI 30 kg/m or BMI 27 kg/m with conditions such as: Type 2 diabetes High blood pressure Fatty liver Obstructive sleep apnea High cholesterol PCOS Knee osteoarthritis For Asian Indians , treatment decisions may be individualized because obesity-related complications often occur at lower BMI values

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Abstract The prevalence of type 2 diabetes (T2D) is increasing worldwide, with many patients developing long-term complications that affect their cardiovascular, urinary, alimentary, and other systems

Butyrate and propionate reduce systemic inflammation by lowering IL-6 and T-NF