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Aerobic exercise has the potential to upregulate the level of miR-146a in serum, which may mitigate vascular tumor necrosis factor receptor-associated factor (TRAF) and TLR4 pathways, thereby attenuating vascular inflammation and damage in atherosclerosis (Wu et al., 2014)

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Daily life stress, exposure to environmental toxins, physical and mental stress, and an overworked immune system all contribute to increased oxidative stress, emphasizing the need to maintain adequate antioxidant levels such as glutathione