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Think of free radicals like sparks from a fire

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Oral L-carnitine has lower bioavailability than injectable forms (approximately 15-25% absorption versus near-complete absorption for injectables), which is why oral doses need to be higher

After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached