It is particularly effective when combined with another topical prescription medication, tretinoin, to enhance its absorption (and means that it can be applied once daily versus the normal twice daily application, and without the use of microneedle devices)
Those impressive clinical trial outcomes come from prescription medications that go directly into your bloodstream, not herbal supplements sitting on your skin
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Yaribeygi, H., Jamialahmadi, T., Moallem, S.A., Sahebkar, A