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The cleavage is mediated by furin peptidase at the S1/S2 site of the spike protein, and by transmembrane protease serine 2 (TMPRSS2) at the S2 site within the S2 domain, as shown in human airway cells 10 ( Figure 2 )

Michael DEmden: Has received honoraria for attendance at national advisory boards, presentations and/or support to attend international meetings from Boehringer Ingelheim, Eli Lilly, AstraZeneca, Novartis, Abbott, Novo Nordisk, Servier and Bayer

14 Conversely, hypertrophied AT secretes inflammatory adipokines that attenuate fibroblast-mediated collagen production in vitro

GHK, a tripeptide known for its role in tissue regeneration and wound healing, was tested for its effects on bleomycin-induced fibrosis