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In diabetic patients, hyperglycemia and other metabolic abnormalities cause oxidative stress and mitochondrial damage in renal TECs, thereby activating apoptotic pathways

Constipation occurred in 16.9% versus 20.2%, diarrhea in 16.9% versus 19.2%, and dyspepsia in 0.7% versus 1.6%

The results revealed that all GPX4 isoforms are expressed in this cell line and, more interestingly, that their absolute abundance followed the same sequence observed in HT22 cells, though in this case the amount of the most prominent isoform, namely c- GPX4 , was notably higher (about four orders of magnitude) than any other isoform