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On the other hand, the investigation of DPP-4 inhibitors as potential anti-cancer agents was not discouraged by this study because DPP4 expression in TC was demonstrated to be associated with cellular invasion, promoting TC cell metastasis, and a more aggressive disease in papillary TC (Lee et al., 2017

What they did: Obese mice received AOD-9604 orally (via gavage) for 14 days at various doses (50, 250, 500 g/kg)

Methionine then undergoes a process called the one-carbon cycle to produce S-adenosyl-l-methionine (SAMe), a major methyl donor which plays an essential role in producing neurotransmitters

In clinical studies of Ulcerative Colitis, it helps both with healing the mucus lining of the colon as well as alleviating inflammation