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Microglia in Alzheimers disease
Retarutide (LY3437943) is a triple agonist peptide of glucagon receptor (GCGR), glucose-dependent insulin-promoting peptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R)
In addition, the inhibition of aspartate aminotransaminase GOT1 promotes labile iron release in PDAC through NCOA4-dependent ferritinophagy, highlighting GOT1 as a therapeutic target through the promotion of PDAC ferroptosis [24]
Extreme Mech Lett 42:101148 Choi YJ, Lee WS, Lee EG, Sung MS, Yoo WH (2014) Sulforaphane inhibits il-1beta-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of mmps, cox-2, and pge2
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