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65 Thus, gain of detrimental effects is likely to be context-dependent and unique to specific situations and effective treatment will require understanding the distinctive situations under which they arise

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Haemophilus influenzae and Lactococcus lactis cannot make GSH but scavenge it from the environment to boost oxidative defense

Recent research further demonstrates that CAT suppresses Hypoxia-inducible factor-2 alpha (HIF-1) expression via activation of solute carrier family 2 member 1 (SLC2A1), effectively reducing ferroptosis-dependent chondrocyte damage and mitigating OA progression (Guan et al., 2023)