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These include Alzheimers Disease where neuroprotective effects are under investigation followed by stroke under similar notion (125) Futhermore, in non-alcoholic fatty liver disease (NAFLD) they show evidence of improved liver histology and hepatic steatosis (126) in PCOS they may help in regulation of weight, reproductive and metabolic parameters simultaneously (127) GLP1-Ras are also under study with their ability to modulate the hemodynamic and inflammatory pathways to treat CKD (128) and Heart failure (129)

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In one of the focus groups, there was no disagreement when one participant asked, [d]oes it feel almost inevitable that those drugs are going to become part of our formulary? Our insurance provider, Cigna told us that within the next 9 to 12 months, theres really not going to be a choice, that all insurance companies are probably going to be covering GLP-1s for weight loss. Occupational health manager, large manufacturer The use of GLP-1 drugs for weight loss is still new for many employers, and many are not sure how or whether they can manage the benefit