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This indication was followed in 2016 by the approval for treatment of ROS1 -positive metastatic NSCLC (comprising about 1% of this tumor type), and more recently, in May 2018, by a breakthrough therapy designation for the treatment of patients with metastatic NSCLC with MET exon 14 alterations (about 34% of all NSCLC) progressing after a previous platinum-based chemotherapy

Triple the peptide, triple the water, same concentration

Standard syringes without half-unit markings require visual interpolation between the 30-unit line and the next marking

In UK clinical settings, the recognised standard diluent for injectable medicines is Water for Injections BP (single-use, preservative-free), and the choice of diluent must always follow the licensed product's Summary of Product Characteristics (SmPC)