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301 Amyotrophic lateral sclerosis and frontotemporal dementia Amyotrophic Lateral Sclerosis (ALS) is characterized by the loss of motor neurons in the cortex, brainstem, and spinal anterior horn

Supplementary Figure 5 Enrichment analysis of upregulated and downregulated pathways

In an attempt to understand how this balance is maintained, it is important to consider some of the sources of reducing or oxidizing equivalents that occur from disulphidebond formation within the ER lumen (Fig 1)