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The B12-producing bacteria that used to populate our soils have been depleted through modern agricultural techniques, meaning that even grazing livestock is unlikely to get enough B12 for us to absorb efficiently by consuming animal-derived food

Neither has published long-term hard-outcome data such as cardiovascular events or mortality, which is the kind of evidence that ultimately defines a metabolic drugs value

Supplement Success Rates High-dose oral supplements (1000-2000 micrograms daily) prove effective for many patients with mild to moderate deficiency

If small particles remain, continue gently swirling until fully dissolved