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Last updated May 2011 (EMA) Because of its deep red color, hydroxocobalamin may cause haemodialysis machines to shut down due to an erroneous detection of a 'blood leak'

Bacteriostatic water's 0.9% benzyl alcohol preservative prevents bacterial growth in reconstituted solutions, extending stable storage from 72 hours to 28-30 days when refrigerated

It doesn't require specific timing relative to meals, though many researchers administer it on a consistent weekly schedule (e.g., every Sunday evening) to simplify adherence tracking

Even with b12 deficiency, this pathway continues functioning at reduced efficiency rather than stopping completely