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"So I switched from honey to hazelnut, which is a more natural look," said Stout

But here's the kicker: dehydrated cells slow down detoxification and diminish glutathiones efficacy

These are common Herxheimer reaction symptoms and can be extremely uncomfortable to deal with

For measurement of metabolite levels in cells, hepatocytes were harvested by treating with 0.25 % trypsin (Gibco #25200), washing with ice-cold PBS to remove trypsin, suspending released hepatocytes in ice-cold PBS, and centrifuging the cell suspension at 1600 g for 10 min at 4 C to obtain the pelleted cells, which were immediately frozen and stored at 80 C for later analysis