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Do not use while pregnant or nursing without medical guidance

The agency has issued warning letters to companies distributing active pharmaceutical ingredients, such as retatrutide and certain other GLP-1 drugs.) Salt forms of semaglutide are not FDA-approved and should not be used in compounding, so practices should ensure any compounding pharmacies they work with do not use salt forms of the active pharmaceutical ingredients

[9] [12] The medication is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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