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Biocatalytic methylation using engineered methyltransferases enables efficient modification of fisetin, leading to improved solubility, chemical stability, and lipophilicity, thereby enhancing its development and application (330)

Given that stress can be considered as a byproduct of exercise and that ashwagandha supplementation improves human physical performance, the adaptogenic qualities of ashwagandha raise the prospect that it could be a useful ergogenic aid

Interestingly, one Smad7 antisense oligonucleotide, mongersen, was recently shown in a double-blind controlled trial to enhance the 15-day remission rate versus placebo in patients with Crohns disease (Monteleone 2015)