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In healthy tissue, the CD47 cloak prevents phagocytic clearance, prolonging circulation, while in the diseased brain the CD47 is cleaved, exposing the NPs to microglial phagocytosis

This represents a limitation for our work and the conclusions that can be drawn from it, particularly for some specific micronutrients for which the oncoprotective or pro-oncogenic role remains unclear

Overall, while herbal medicine presents promising avenues for managing PCOS-related metabolic and hormonal imbalances, the existing evidence remains mixed