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495 Platelet granuleplasma membrane fusion is analogous to exocytosis in neurons, where detailed studies have shown the importance of a core set of integral membrane proteins called soluble N -ethylmaleimide-sensitive factor (NSF) attachment protein receptors (SNAREs)
In the detection of pro-inflammatory factor secretion, we also found that OGD treatment promoted the expression of pro-inflammatory factors, indicating that the inflammatory response was enhanced (Figure 3H)
When pretreated with antibodies to integrins alpha 1 and beta 1, MSC failed to produce an increase of VEGF, which indicated that the effects of GHK on secretion of trophic factors by MSC involve the integrin cellular pathway [30]
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