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Conclusion Stopping glutathione supplements can result in a gradual reversal of benefits like skin whitening, reduced oxidative stress, and enhanced immunity

(Source 1) Suboptimal and deficient glutathione levels are associated with aging and an increased risk for chronic diseases, including: Mitochondrial dysfunction Neurodegenerative disease, including Alzheimers and Parkinsons disease Cancer Chronic liver disease Metabolic disease, including diabetes and hypertension Cardiovascular disease Pulmonary Infertility Autoimmune diseases, including lupus and multiple sclerosis Mental health disorders Cystic fibrosis (Source 1, 2) A viral illness, including SARS-CoV-2, the virus that causes Covid-19, can also cause glutathione deficiency

As we age, the levels of glutathione in our bodies tend to decrease, which can contribute to oxidative stress and various health issues, including skin aging

Oxidative stress: new insights on the association of non-alcoholic fatty liver disease and atherosclerosis