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Use the formula: V draw = D anchor V water M anchor D anchor is your target dose in mg, V water is the BAC water volume you reconstitute with in mL, and M anchor is the anchor compound mass in the vial in mg
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We dont know about possible interactions with medications or long-term risks
Overall, across the two repeat experiments for Cagri and CagriBB bound to the CTR, the conformational equilibrium between the bypass vs CT-like state was similar, suggesting that the salt bridge/ionic lock is sufficient to preferentially stabilize the bypass conformation at CTR (Supplementary Fig
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