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Edwards CA, Lofty JR

Diagnosis: PCOS: increased pregnancy rates (15 RCTs, 1,908 women) Unexplained fertility: no difference in pregnancy rates (4 RCTs, 997 women) Tubal: no difference in pregnancy rates (2 RCTs, 71 women) Poor responders: no difference in pregnancy rates (1 RCT, 65 women) Poor ovarian reserve: no difference in pregnancy rates (2 RCTs, 266 women) Endometriosis: no difference in pregnancy rates (1 RCT, 280 women) Adverse events: Miscarriage: no difference (24 RCTs, 3,229 women) Multiple pregnancy: no difference (9 RCTs, 1,886 women) Ectopic pregnancy: no difference (7 RCTs, 308 women) Preterm birth: no difference (2 RCTs, 220 women) Placenta previa: no differences (1 RCT, 180 women) Preeclampsia: no difference (1 RCT, 160 women) N-acetyl-cysteine (NAC) NAC is a medication that can be used to treat Tylenol (acetaminophen) overdoses by increasing levels of the antioxidant glutathione

Women who are pregnant or nursing should also stay away from GLP-1 agonists because it is unclear how they will affect the growth of the fetus or the supply of breast milk

S., Coman, D