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[11] You should also seek urgent medical advice for physical symptoms that could indicate serious side effects of Rybelsus, including: Severe, persistent upper abdominal pain (with or without vomiting) which could indicate pancreatitis Symptoms of gallbladder disease such as pain in the upper right abdomen, fever or yellowing of the skin/eyes Inability to keep fluids down or signs of dehydration Sudden changes in vision, which could relate to diabetic retinopathy complications When discussing concerns with your healthcare provider, be prepared to provide information about: When symptoms started in relation to beginning Rybelsus Severity and frequency of mood changes Impact on daily functioning and quality of life Any previous history of mental health conditions Other medications you are taking Recent life stressors or changes Your healthcare team can conduct a thorough assessment to determine whether symptoms are related to Rybelsus, your diabetes, other factors, or a combination

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