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Melatonin increases NMDA receptor subunits 2A and 2B concentrations in rat hippocampus

In the beagle dog model induced by the combination of alloxan and STZ, the levels of BNIP3, NIX, and FUNDC1 were significantly upregulated, indicating that DKD can induce non-ubiquitin-dependent mitophagy, and N-acetyl-L-cysteine (NAC) treatment reduced the levels of BNIP3, NIX, and FUNDC1, suggesting that NAC can alleviate mitophagy and reduce kidney damage in DKD [154]

Taking medications too close together may amplify interaction risks

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