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Because the drugs seem to dampen inflammation in the brain, theyre now being studied as a possible way to prevent neurological diseases like Parkinsons and Alzheimers, too

To date, the presence of GLP-1R in the renal vasculature has been confirmed but not in the tubules ( Oxidative Stress/Inflammation GLP-1RAs have been shown to prevent renal oxidative stress by inhibiting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase through the activation of PKA and the production of cyclic adenosine monophosphate (cAMP)

And theres lots of examples in medicine where the theory doesnt quite translate into a therapeutic

PGC-1 is a common target of the two metabolic sensors, and has been shown to have protective effects in patients with metabolic diseases [29]