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It is an active and complex battlefield that has been fighting these wars for years

Prevention of vitamin B12 deficiency in people who need more vitamin B12 than usual due to certain conditions (such as pregnancy, thyroid problems, liver or kidney problems)

[DOI] [PubMed] [Google Scholar] 36.Shi XL, Ye JP, Leonard SS, Ding M, Vallyathan V, Castranova V, Rojanasakul Y, Dong ZG

Key priorities include doseresponse optimization for acute versus chronic phases, inclusion of biomarkers such as glutathione reductase activity, neuroinflammatory cytokines, and imaging-based lesion metrics, and development of formulations that improve central nervous system bioavailability