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JACC Basic Transl Sci 9(8):10411052 Haghighi K, Kolokathis F, Gramolini AO, Waggoner JR, Pater L, Lynch RA, Fan GC, Tsiapras D, Parekh RR, Dorn GW 2nd, MacLennan DH, Kremastinos DT, Kranias EG (2006) A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy
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Research suggests the tripeptide acts as a copper transport molecule, delivering bioavailable copper to tissues where it participates in enzymatic reactions critical for connective tissue remodeling