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Several published studies have reported an association between ghrelin and obesity, with plasma ghrelin levels negatively correlated with BMI [97] and IR [98, 99]

The World Health Organization Classification specifies lung cancer precancerous lesions as squamous epithelial atypia and carcinoma in situ , atypical adenomatous hyperplasia, and infiltrative idiopathic pulmonary neuroendocrine cell hyperplasia, which are the early warning signals for the development of lung cancer (Kerr, 2001)

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