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Participants who took 2.4 mg of semaglutide weekly lost an average of 14.9% of their body weight over 68 weeks (about 16 months), compared to 2.4% in the placebo group

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PIONEER 5 The PIONEER 5 study enrolled patients with T2DM and moderate renal impairment (estimated glomerular filtration rate [eGFR] of 3059 mL/ min/1.73 m 2 ) to examine the efficacy and safety of oral semaglutide in patients with compromised kidney function