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Tf extracted from human serum, or genetically engineered (Bobik et al., 2019), can be used as a natural iron-chelating agent to treat iron overload in specific parts of the body

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29,30 In 1985, oxidative stress was defined as a cellular imbalance between oxidants and reductants, leading to the differentiation of eustress and distress to describe oxidative stress states under physiological and pathological conditions, thereby advancing our understanding of oxidative stress in human diseases

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