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This is supported by the companys focus on expanding its MC4R franchise into adjacent areas, such as acquired hypothalamic obesity to drive growth [59]

Further research is needed to determine whether the anti-inflammatory effects of GLP-1 analogs are more pronounced compared to DPP4i, though the identified effects on TNF, IL1B and IL6 do provide overlap with those pathways engaged in RA, and provide an area of focus for future studies

Gradual dose escalation over 4-8 weeks allows assessment of individual response and tolerance