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expounded on the obesity paradox, suggesting increased BMD is offset by poor bone quality due to advanced glycation end-products (AGEs) accumulation, impaired osteoblast function, and uncoupled bone turnover favoring resorption

MIC B12 shots are known to not only reduce fat, but also possibly increase metabolism

doi: 10.1016/j.bbi.2009.11.002 68 HuXLiPGuoYWangHLeakRKChenSet al

Specific clinical scenarios where injections are the standard of care include pernicious anemia, severe malabsorption syndromes, post-bariatric surgery when oral supplementation has failed, and critically low serum B12 levels accompanied by neurological deterioration