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In patients with bulimia or anorexia nervosa, vitamin B 12 deficiency also can be related to diet

It exists in either a reduced or an oxidized form where the two cysteine residues are linked in an intramolecular disulfide bond

Dietary supplementation with glycine to Phase-II HSB increased concentrations of guanidinoacetate in the plasma by 15% and 31%, respectively (Table 1)

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