Research interest in BPC-157 has expanded considerably due to its demonstrated effects in numerous animal models, showing potential in tissue repair, wound healing, and organ protection
Asrih M, Altirriba J, Rohner-Jeanrenaud F, Jornayvaz FR
SCFA are considered as possible mediators of the communication between gut microbiota and the brain (Dalile et al., 2019)
In an open-label, phase 3, multicenter study involving 11 children aged 25 years with biallelic POMC, PCSK1, or LEPR variants, or genetically confirmed BardetBiedl syndrome (BBS), 83% achieved a 0.2-point reduction in BMI Z score over 52 weeks, with a mean BMI reduction of 18% observed overall (26% in the POMC/LEPR group and 10% in the BBS group) [45]