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The purified and prepared freeze-dried powder is 1.31g, the calculated yield is 33.5 percent, and the purity is 96.75 percent The purification analysis method comprises the following steps: c18 chromatographic column Gradient: mobile phase MPA 0.1% TFA MPB 95% acetonitrile

10.1186/s12933-021-01317-3 Summary Keywords c-GAS-STING pathway activation, defective lipid metabolism, diabetic kidney disease, inflammation, mitochondrial damage and dysfunction, podocyte-ANGPTL4, tubule-ANGPTL4 Citation Srivastava SP, Arora AV, Hamed M, Urval A, Dupati A, Xia S, Yoshida S and Inoki K (2026) Kidney angiopoietin-like protein 4 regulates fibrotic responses in diabetic kidney disease

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Complementary interventions Physical therapy: Perhaps the most important complementary intervention