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doi: 10.1016/j.nbd.2012.12.017

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What We Dont Know About Oral Drops Key unknowns include: Long-term safety True potency Risk of overdose or underdosing Hormonal and metabolic consequences over time Compounding-Specific Risks Compounded medications may carry: Inconsistent dosing Variability between batches Contamination risk Limited post-market surveillance Related Read: Switching from Compounded GLP-1s to FDA-Approved Medications: What You Need to Know Evidence Gaps and Research Status At present: No large human trials confirm oral tirzepatide drops are safe or effective Most data are extrapolated from injectable use or early research Lack of evidence does not mean safety Clinical caution is warranted

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