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544 In addition, emerging targets such as IL-36 pathway inhibitors promote Treg cell proliferation by neutralizing the proinflammatory effects of IL-36, and TLR4/MyD88 small molecule inhibitors provide a new way of treating UC by modulating innate immune hyperactivation triggered by colony dysregulation

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Glutathione exists in 100 M concentrations as glutathione persulfide (GSSH) [104], the latter exhibiting higher activities due to its higher nucleophilic power than GSH [105]