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Two studies were published in the impactful New England Journal of Medicine [Reference Weghuber, Barrett and Barrientos-Prez1,Reference Arslanian, Hannon and Zeitler2], research motivated, as noted by the authors, in no small measure precisely because the currently approved medications for pediatric obesity and type 2 diabetes have proven to be limited in their effectiveness and fraught with adverse events [Reference Woodard, Louque and Hsia3]