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Identification of membrane-type receptor for bile acids (M-BAR) Biochem Biophys Res Commun

This is a non-negotiable contraindication based on the boxed warning

Oct 2011;25 Suppl B:22B-28B

While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood