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Escobar-Morreale HF, Alvarez-Blasco F, Botella-Carretero JI, Luque-Ramirez M

As a key commensal bacterium for maintaining gut barrier integrity, the reduction of Akkermansia may exacerbate hyperandrogenemia and ovulatory dysfunction in PCOS by increasing LPS translocation, triggering ovarian macrophage pyroptosis and interferon- (IFN-)-mediated inflammatory responses, thereby disrupting steroid hormone synthesis, promoting granulosa cell apoptosis, and exacerbating hyperandrogenemia and ovulatory dysfunction in PCOS

Orthologous groups are divided into 26 functional categories covering key cellular processes such as information storage and processing, metabolism, and general cellular functions, providing a high-level functional overview that is especially useful for newly sequenced genomes or non-model organisms with limited annotation

This all goes hand-in-hand with anti-aging benefits and overall general improved levels of wellbeing