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Studies have shown that NAD switches off the genes of aging, helping to extend life span, increases endurance, improves cognitive function, and enhances cellular energy

Research demonstrates thymosin beta-4 suppresses activation of NF-B, a key inflammatory transcription factor, in macrophages and other immune cells

In tendon and ligament repair research, the blend is used in combination protocols that aim to engage both cytoskeletal remodeling (TB-500's contribution) and angiogenic and growth-factor pathway activity (BPC-157's contribution) simultaneously

Proton pump inhibitors (acid blockers) and over-the-counter non-steroidal anti-inflammatory agents can change the environment of the GI tract predisposing to nutrient deficiencies Unfortunately, that isnt an exhaustive list, but it does give you a pretty good idea of why you should be concerned about your vitamin B12 levels