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Both AOPPs and AGEs possess similar structures that induce comparable biological effects, and their accumulation in biological systems leads to similar clinical consequences

"Some people will say things like, 'Oh, when I started regaining weight, it seemed like I just smell food, and I gained more weight.' That's an exaggeration, of course, but it can certainly feel that way given the pace of how quickly some people can regain weight." In addition, as with weight loss, many variables affect weight gain, some of which we can control, some of which we can't

doi: 10.2147/DDDT.S100534

Preclinical Insights into GLP-1 Receptor Modulation of Addictive Behaviors Building on the mechanistic insights discussed above, this section reviews preclinical evidence supporting the role of GLP-1 receptor agonists in modulating addiction-related behaviors through central pathways