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26,29,30,31 Acute precipitated withdrawal In Experiment 1, to establish the model and validate the behavioral scoring, pups were randomized within litter to receive either naloxone hydrochloride (1 mg/kg, intraperitoneal (i.p.)), a dose that has been shown to precipitate acute withdrawal in rats, 26,29,30,31 or an equal volume of saline

R.et al (2009)

In LepR-deficient Koletsky rats, the adenovirally induced expression of LepRs in ARC nucleus improves peripheral insulin sensitivity via enhanced suppression of hepatic glucose production, with no change in insulin-stimulated glucose uptake or disposal

L-carnitine is an important nutrient that acts as a transport for fatty acids, essential for the cellular production of energy