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doi: 10.1155/2017/8416763 171 AcevesCAnguianoBDelgadoG

It not only shortens the time for making bread to one half or one third of the original time, greatly improves the working conditions, and plays a role in strengthening food nutrition and other functions

It occurs in two main phases, firstly a cartilage template is formed in a non-vascularised environment, and then subsequently this template is gradually replaced by bone tissue through the formation of the periosteum, which harbours immature osteoprogenitor cells that differentiate into osteoblasts