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POTENTIAL THERAPEUTIC ROLE OF MELATONIN IN HEPATOBILIARY DISEASES: CURRENT EVIDENCE AND CLINICAL OBSERVATIONS 2Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland INTRODUCTION The modern history of melatonin (MEL) begins in the twentieth century with a study by McCord and Allen (1) from 1917 which showed that the pineal gland homogenate contained a substance that lightened the skin of tadpoles