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Semaglutide works by mimicking the action of glucagon-like peptide 1 (GLP-1), a naturally occurring hormone that has the following effects: Stimulates insulin production to help regulate blood sugar Inhibits glucagon release, slowing the release of sugar into the blood, causing the body to burn more fat Slows gastric emptying to make you feel full longer Reduces appetite (because you feel full) Together, these effects can help you slow the conversion of sugar to fat, burn more fat, feel less hungry, and adhere to a healthy diet, all of which make managing weight and blood sugar easier

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It acts upstream in the brain, which can shift arousal in a different way than pills

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