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Drug manufacturers oppose the move, warning it creates a loophole around the years of clinical trials normally required to approve a medication

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Am J Physiol Lung Cell Mol Physiol 291 : L46L57 Hu S, Zhao H, Al-Humadi NH, Yin XJ, Ma JK 2006 Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway

In preclinical work, BPC-157 has been evaluated in cell-based and animal models, in which investigators examine tissue integrity, barrier function, and responses to experimentally induced stress or injury under controlled conditions