In his review of this history, Klatt points to two bellwether moments President Eisenhowers heart attack in 1955 and a 1961 Time Magazine cover warning of the dangers of fat intake and heart disease that alerted Americans to the prevalence of cardiovascular disease as a new threat facing Americans, as the risk of death from infectious disease waned
Eat small, frequent, nutrient-dense meals to maintain steady blood sugar and calorie intakeskipping meals or under-eating during the adjustment phase intensifies tiredness
Other notable adverse effects include: Injection site reactions such as erythema, pruritus, or swelling Fatigue reported in approximately 5% to 6% of patients Hypoglycemia when used in combination with insulin or sulfonylureas Increased heart rate with modest elevations of 2 to 4 beats per minute (a class effect of incretin therapies with uncertain clinical significance) Serious but rare adverse effects include acute pancreatitis, gallbladder disease (cholelithiasis, cholecystitis), acute kidney injury (typically secondary to dehydration from gastrointestinal symptoms), and hypersensitivity reactions
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