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Preventing Fetal Oxidative Stress Because of the demand for oxygen and nutrients in fetal development, there is a greater risk of oxidative stress during pregnancy

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Experiments were performed in triplicates

Patients with Chronic Pulmonary Disease: Hydrocodone bitartrate and acetaminophen tablet-treated patients with significant chronic obstructive pulmonary disease or cor pulmonale, and those with a substantially decreased respiratory reserve, hypoxia, hypercapnia, or pre-existing respiratory depression are at increased risk of decreased respiratory drive including apnea, even at recommended dosages of hydrocodone bitartrate and acetaminophen tablets (see WARNINGS, Life-Threatening Respiratory Depression)