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Available evidence supports the cautious reintroduction of sulfonamide antibiotics via desensitization, which is usually well tolerated and should be considered in those with strong indications for trimethoprim-sulfamethoxazole and a reported sulfonamide allergy

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Correspondingly, treatment of HZRG also decreased LCA, isoLCA and 6-ketoLCA levels of the NASH mice (Figure 5G)

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